منابع مشابه
Antidepressants for the treatment of chronic pain.
Chronic pain represents one of the most important public health problems and, in addition to classical analgesics, antidepressants are an essential part of the therapeutic strategy. This article reviews available evidence on the efficacy and safety of antidepressants in major chronic pain conditions; namely, neuropathic pain, headaches, low back pain, fibromyalgia, irritable bowel syndrome (IBS...
متن کاملAntidepressants and antiepileptic drugs for chronic non-cancer pain.
The development of newer classes of antidepressants and second-generation antiepileptic drugs has created unprecedented opportunities for the treatment of chronic pain. These drugs modulate pain transmission by interacting with specific neurotransmitters and ion channels. The actions of antidepressants and antiepileptic drugs differ in neuropathic and non-neuropathic pain, and agents within eac...
متن کاملUse of antidepressants in the treatment of chronic pain.
There is a high prevalence of chronic pain disorders in the population and the individual and societal costs are large. Antidepressants have been used in the treatment of chronic pain and the pain-relieving effects are independent of the mood-elevating properties. We reviewed randomised-controlled trials, systematic reviews and meta-analyses of antidepressants in the treatment of chronic pain d...
متن کاملAntidepressants as Potential Adjuvants in Treating Chronic Pain and Pain Induced Depression
Clinical studies have shown that people suffering from chronic pain are often also burdened by depression. Antidepressants are widely used to treat painful chronic rheumatic conditions but, contrary to neuropathic conditions, however, little is known about their mechanisms of action. This article reviews the available evidence on the efficacy and safety of antidepressants in major chronic pain ...
متن کاملNeuronal and immunological basis of action of antidepressants in chronic pain - clinical and experimental studies.
The current knowledge of the pharmacological actions of the tricyclic antidepressants (TCAs) has slowly evolved through their over 40-year history. Chronic pain represents one of the most important public health problems, and antidepressants are an essential part of the therapeutic strategy in addition to classical analgesics. This article reviews the available evidence on the efficacy and safe...
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ژورنال
عنوان ژورنال: BMJ
سال: 1997
ISSN: 0959-8138,1468-5833
DOI: 10.1136/bmj.314.7083.763